This essay centers on the notion of the symbolic and its impact as developed by Claude Lévi-Strauss in his Introduction to the Work of Marcel Mauss. I examine Lévi-Strauss’ formulation of the “floating signifier” and its influence in French thought, particularly in the work of Jacques Lacan and Jacques Derrida. In doing so, I argue that Lévi-Strauss’ notion may be a misreading of the structural linguistics of Ferdinand de Saussure that has important implications for contemporary political issues on the left (...) in both theory and practice. (shrink)

This essay reads acclaimed poet James Galvin’s 1992 semi-autobiographical novel through the lenses of Martin Heidegger’s notion of authenticity and Patrick Wolfe’s discussion of settler-colonialism. I argue that Lyle, arguably the novel’s main character, is portrayed as living “authentically” in contrast to the deep inauthenticity of Ferris. I connect Western authentic dwelling with settler-colonial logic, centering my account on the figures of the “lazy” and “magical” “Indian.” Ultimately, I find that far from rejecting settler-colonial logic Galvin’s text plays out of (...) a return of the repressed of the present absence of indigenous persons in the land and the text. (shrink)

Topics in Cognitive Science, Volume 13, Issue 1, Page 128-141, January 2021.

Today there are multiple implantable medical devices on the market. The type of implants that interface the body’s tissues has been considered to have particular strong ethical implications. This article describes a development of a novel practice for ethical assessment and reflection within medical device research and development of non-CE marked medical devices, taking the perspective of both the ethicist and the researcher. The research case was an EU funded project where the aim was to develop and compare the efficiency (...) of invasive and non-invasive technological medical devices to create meaningful sensations as a novel therapy for phantom limb pain. An Independent Ethical Advisor with a regulatory and advisory role was assigned to the project, allowing us to investigate the projects deliberate incorporation of ethics. In the article we suggest and applied a novel framework based on action research for combining ethical assessment with building ethical reflection. The case analyse five different activities / elements: 1) the use of informed consent; 2) a survey amongst the research partners; 3) a workshop session; 4) observation of consortium meetings; and 5) an interview with a participating patient. (shrink)

Shapes that are rendered invisible through backward masking are still able to influence motor responses: this is called masked priming. Yet it is unknown whether this influence is on the control of ongoing action, or whether it merely influences the initiation of an already-programmed action. We modified a masked priming procedure such that the critical prime-mask sequence was displayed during the execution of an already-initiated goal-directed pointing movement. Psychophysical tests of prime visibility indicated that the identity of the prime shapes (...) were not accessible to participants for conscious report. Yet detailed kinematic analysis of the finger in motion revealed that masked primes had an influence on the pointing trajectories within 277 ms of their appearance, 56 ms earlier than the trajectory deviations observed in response to the visible masks. These results indicate that subliminal shapes can indeed influence the control of ongoing motor activity. (shrink)

The RecQ family of DNA helicases have been shown to be important for the maintenance of genomic integrity in all organisms analysed to date. In human cells, representatives of this family include the proteins defective in the cancer predisposition disorder Bloom's syndrome and the premature ageing condition, Werner's syndrome. Several pieces of evidence suggest that RecQ family helicases form associations with one or more of the cellular topoisomerases, and together these heteromeric complexes manipulate DNA structure to effect efficient DNA replication, (...) genetic recombination, or both. Here, we propose that RecQ helicases are required for ensuring that structural abnormalities arising during replication, such as at sites where replication forks encounter DNA lesions, are corrected with high fidelity. In mutants defective in these proteins, not only is replication abnormal, but cells display aberrant responses to DNA-damaging agents or inhibitors of DNA synthesis. We suggest that RecQ helicases may be important for the integration of cellular responses to these insults, such as by linking cell cycle checkpoint responses to recombinational repair. BioEssays 21:286–294, 1999. © 1999 John Wiley & Sons, Inc. (shrink)

Research suggests that the reaching hand automatically deviates toward a target that changes location during the reach. In the current study, we investigated whether movement intention can influence the target jump’s impact on the hand. We compared the degree of trajectory deviation to a jumped target under three instruction conditions: GO, in which participants were told to go to the target if it jumped, STOP, in which participants were told to immediately stop their movement if the target jumped, and IGNORE, (...) in which participants were told to ignore the target if it jumped and to continue to its initial location. We observed a reduced response to the jump in the IGNORE condition relative to the other conditions, suggesting that the response to the jump is contingent on the jump being a task-relevant event. (shrink)

BackgroundThe ARRIVE (Animal Research: Reporting of In Vivo Experiments) guidelines are widely endorsed but compliance is limited. We sought to determine whether journal-requested completion of an ARRIVE checklist improves full compliance with the guidelines.MethodsIn a randomised controlled trial, manuscripts reporting in vivo animal research submitted to PLOS ONE (March–June 2015) were randomly allocated to either requested completion of an ARRIVE checklist or current standard practice. Authors, academic editors, and peer reviewers were blinded to group allocation. Trained reviewers performed outcome adjudication (...) in duplicate by assessing manuscripts against an operationalised version of the ARRIVE guidelines that consists 108 items. Our primary outcome was the between-group differences in the proportion of manuscripts meeting all ARRIVE guideline checklist subitems.ResultsWe randomised 1689 manuscripts (control: n = 844, intervention: n = 845), of which 1269 were sent for peer review and 762 (control: n = 340; intervention: n = 332) accepted for publication. No manuscript in either group achieved full compliance with the ARRIVE checklist. Details of animal husbandry (ARRIVE subitem 9b) was the only subitem to show improvements in reporting, with the proportion of compliant manuscripts rising from 52.1 to 74.1% (X2 = 34.0, df = 1, p = 2.1 × 10−7) in the control and intervention groups, respectively.ConclusionsThese results suggest that altering the editorial process to include requests for a completed ARRIVE checklist is not enough to improve compliance with the ARRIVE guidelines. Other approaches, such as more stringent editorial policies or a targeted approach on key quality items, may promote improvements in reporting. (shrink)

Anthony K. Jensen - Nietzsche's Life Sentence: Coming to Terms with Eternal Recurrence - Journal of the History of Philosophy 44:4 Journal of the History of Philosophy 44.4 671-672 Muse Search Journals This Journal Contents Reviewed by Anthony K. Jensen Emory University Lawrence J. Hatab. Nietzsche's Life Sentence: Coming to Terms with Eternal Recurrence. New York-London: Routledge, 2005. Pp. xix + 191. Paper, $24.95. In his latest book, Lawrence Hatab brings together several threads from his previous writing into (...) an elegant expression that examines a wide range of Nietzsche's thought through the single prism of his notoriously obscure conception of "Eternal Recurrence." The opening chapters establish the affirmation of becoming and the "tragic" view of the world (which Nietzsche had already articulated in his earliest.. (shrink)

With his _An Interpretation of Nietzsche’s "On the Uses and Disadvantage of History for Life_", Anthony K. Jensen shows how 'timely' Nietzsche’s second "Untimely Meditation" really is. This comprehensive and insightful study contextualizes and analyzes a wide range of Nietzsche’s earlier thoughts about history: teleology, typology, psychology, memory, classical philology, Hegelianism, and the role historiography plays in modern culture. _On the Uses and Disadvantages of History for Life_ is shown to be a ‘timely’ work, too, insofar as it weaves (...) together a number of Nietzsche's most important influences and thematic directions at that time: ancient culture, science, epistemology, and the thought of Schopenhauer and Burckhardt. Rather than dismiss it as a mere ‘early’ work, Jensen shows how the text resonates in Nietzsche’s later perspectivism, his theory of subjectivity, and Eternal Recurrence. And by using careful philological analysis of the text’s composition history, Jensen is in position to fully elucidate and evaluate Nietzsche’s arguments in their proper contexts. As such Jensen’s _Interpretation_ should restore Nietzsche’s second "Untimely Meditation" to a prominent place among 19 th Century philosophies of history. (shrink)

Ernst Cassirer Ernst Cassirer was the most prominent, and the last, Neo-Kantian philosopher of the twentieth century. His major philosophical contribution was the transformation of his teacher Hermann Cohen ’s mathematical-logical adaptation of Kant’s transcendental idealism into a comprehensive philosophy of symbolic forms intended to address all aspects of human cultural life and creativity. In … Continue reading Ernst Cassirer →.

Nietzsche stands alone among the great nineteenth-century philosophers of history to have been trained and employed as an historian. As a classical philologist, he was trained not only in Ancient languages, but also in the methods of critical hermeneutics, textual genealogy, and cultural theory. Despite this there has been comparatively little scholarly attention paid to Nietzsche's most pointed reflection on history: _On the Uses and Disadvantage of History for Life _, the second of his _Untimely Meditations_. In this monograph, Anthony (...) K. Jensen demonstrates how ‘timely’ this work of Nietzsche’s is, revealing a text that offers insight into the most important aspects of Nietzsche’s then-contemporary philosophy of history, including teleological theories, Hegelianism, Positivism, romantic historiography, classical philology, and the role of history in education and politics. Using a straightforward and conversational approach, Jensen contextualizes the figures and movements that serve as Nietzsche’s interlocutors, and situates this text within Nietzsche’s larger philosophical project. Through an examination of Nietzsche's views, the author argues for the contemporary philosophical relevance of _On the Uses and Disadvantage of History for Life_, and advances the scholarly discussion of this oft-overlooked but nevertheless essential text. (shrink)

The twelve contributors to this volume embody the best in ancient philosophical scholarship from America and Europe. Each author presents a carefully-wrought argument that adds substantially to the literature in their chosen topics.Carlo Natali’s “Socrates’ Dialectic in Xenophon’s Memorabilia” argues for the internal coherence of Xenophon’s conceptions of dialegesthai and dialektikos, and shows how Xenophon portrays elenchos as one method among several Socrates used to encourage his interlocutors to become better citizens. In the eclectic “If You Know What Is Best, (...) You Do It,” Gerhard Seel argues for a weak form of moral intellectualism, the possibility of a deontological Socratic ethics, and for the restriction of “Socratic” knowledge to meta-ethical claims. Charles H. Kahn briefly shows how Plato wrestled with the popular acceptance of hedonism. The strange acceptance of hedonism in the Protagoras is said to be neither straightforwardly ironical nor exactly a thesis Plato himself outright rejected at that time. Terrence Irwin, in “Socrates and Euthyphro,” examines the difference between “god-beloved” and “pious” in terms of a. (shrink)

This paper aims to reexamine Nietzsche’s early interpretation of Heraclitus in an attempt to resolve some longstanding scholarly misconceptions. Rather than articulate similarities or delineate the lines of influence, this study engages Nietzsche’s interpretation itself in its historical setting, for the first time acknowledging the contextual framework in which he was working. This framework necessarily combines Nietzsche’s reading in philology, post-Kantian scientific naturalism, and of the romantic worldviews of Schopenhauer and Wagner. What emerges is not the acceptance of the metaphysical-flux (...) doctrine so much as a natal form of his physiognomic theory ofperspectivism, a naturalistic and anti-teleological conception of flux, and a theory of justice as cosmodicy. (shrink)

K.J. Devlin has extended Jensen's construction of a model ofZFC andCH without Souslin trees to a model without Kurepa trees either. We modify the construction again to obtain a model with these properties, but in addition, without Kurepa trees inccc-generic extensions. We use a partially defined ◊-sequence, given by a fine structure lemma. We also show that the usual collapse ofκ Mahlo toω 2 will give a model without Kurepa trees not only in the model itself, but also inccc-extensions.

We begin by setting out the posision dubbed 'Fregean descriptivism', that Kripke attributed to Frege. We then set out various descriptivist theses. We proced to argue that Kripke’s interpretation of Frege as a reference-fixing descriptivist stems from his ascription of two other views, each logically weaker than reference-fixing descriptivism itself, to Frege. These are sense descriptivism and the view that sense fixes reference. The meaning descriptivism and the reference-fixing descriptivism of Kripke’s Frege have sense descriptivism as their common, logically weaker, (...) core. Since we do not concur with Kripke’s view that Frege was a sense descriptivist, we do not share his reasons for thinking that Frege was a reference-fixing descriptivist. (shrink)

Organizational change surrounding the security of identifiable health information has become imperative. This is a significant challenge for managers who are held responsible for loss of privacy through faulty security procedures. Management cannot completely secure the organization and still provide employees and customers with the information and services they need. Organizations must decide how much and what type of security they need, how to assign priorities, and how to manage security as the organization evolves in a competitive environment.

Name der Zeitschrift: Nietzsche-Studien Jahrgang: 44 Heft: 1 Seiten: 462-486.

In the final section of their work Empire, Hardt and Negri discuss the coming into being of the multitude, the unified force that overthrows the system of ‘Empire’. Absent from the account of this unification of the multitude is the influence of religion. I endeavor to show that contrary to Hardt’s and Negri’s assumption, religion is not dissipating among the multitude and that its impact will be contrary to the creation of a unified multitude. Thus the creation of the unified (...) multitude requires an absence of religion, but the creation of the multitude under the system of Empire entails a creation of more theists, leading to a seeming contradiction in the process of creating a unified multitude. In order for the creation of the multitude envisioned by Hardt and Negri to be complete, the issue of religion must be addressed, it cannot simply be assumed away as unimportant or non-existent. (shrink)

In contrast to positivistic assignations of influence in Nietzsche-studies, this article considers the possibility of “conversational” reconstructions of contexts, where the focus is less on “whether” and “when” Nietzsche read a text, and concentrates instead on “how” and “why” he read it. This method is exemplified by the case of Philipp Mainländer, a contemporary about whom Nietzsche says almost nothing of philosophical importance. This article shows that six key leitmotifs of the Zarathustrazeit happen to form direct solutions to dangers entailed (...) by Mainländer’s system: the Death of God, the Übermensch, the Last Man, Will to Power, Eternal Return, and Amor Fati. That each of these tropes serves as a neat solution to Mainländer suggests that Nietzsche was engaged in a sort of competitive intellectual conversation with his philosophy. And as such, Mainländer’s influence on Nietzsche, even if mostly negative, should not continue to be neglected. (shrink)

Nietzsche’s break from Schopenhauer is usually regarded as coextensive with his movement toward ontological naturalism, the view that all there is is limited by the scope of what is naturally observable. Moral norms like good and evil are accordingly ruled out as “things,” but naturalized as human, all-too-human constructions, just as much as are God and the soul, just as much as would Schopenhauer’s non–naturally observable one world Will. While I think that basic picture is correct, I also think that (...) scholars have regarded the problem with insufficient attention to the historical context of that transition, especially when it comes to naturalistic explanations of choice and agency. The move away from a.. (shrink)

This article exams the philosophy of history of the now mostly-forgotten 19th Century philosopher, Eduard von Hartmann. Hartmann inverts Hegel’s rational teleology by his reliance on a notion of ‘unconscious ideas’. Purposes are a species of idea. All natural things, including unintelligent natural things, will purposes of which they are often not conscious. These unconscious ideas cannot be held by natural beings that lack intellect, so there must be some supra-naturalistic being, which Hartmann names the Metaphysical Unconscious, that imposes purposes (...) on unconsciously-acting agents. The course of human history is the gradual becoming-conscious of the ends posited by the Metaphysical Unconscious. Insofar as nature always achieves the purposes of the Metaphysical Unconscious this is the best of all possible worlds. Insofar as those purposes are realized irrespective of human happiness, historical progress becomes the gradual assurance of human misery. (shrink)

Resumo: A Segunda consideração extemporânea geralmente é tida em conta por filósofos e historiadores, em razão de sua crítica ao que Nietzsche classifica como “doença histórica”,. Isso por uma boa razão: a crítica de Nietzsche tem como alvo não apenas a famosa tríade composta por historiadores monumentais, antiquários e críticos, mas também suas modalidades contemporâneas em historiografia e teleologia científicas. O que frequentes vezes é desconsiderado é que o próprio Nietzsche expõe - ainda que numa retórica altamente estilizada - uma (...) concepção afirmativa da história. Essa concepção, como eu proponho, faz o leitor retornar ao enunciado que inaugura o livro, qual seja, o Ceterum Censeo, de Goethe. A demanda de Nietzsche de que a história serve à vida é uma nova aplicação da teoria de Goethe do crescimento morfológico como consequência de forças polares concorrentes para o reino da história. Uma vez que Goethe tinha os organismos vivos como a crescer por meio de forças em concorrência, também Nietzsche entendia que os indivíduos e culturas cresciam por meio de uma história considerada, acima de tudo, uma espécie de arena competitiva em que se expressam impulsos antagonistas.: The second Untimely Meditation is usually regarded by philosophers and historians for its critique of what Nietzsche labels ‘historische Krankheit’. This is for good reason, as Nietzsche’s critique not only targets the famous triad of Monumental, Antiquarian, and Critical historians, but also his contemporary fashions in scientific historiography and teleology as well. What is too often overlooked is that also Nietzsche exposits -- albeit in highly-stylized rhetoric -- an affirmative vision of history. This vision, I argue, returns the reader to the opening sentence of the book, namely, the Ceterum Censeo from Goethe. Nietzsche’s demand that history serve life is a novel application of Goethe’s theory of morphological growth as a consequence of polar competing forces to the realm of history. As Goethe thought living organisms grow by means of intrinsic competitive forces, so Nietzsche thought individuals and cultures grow by means of a history that is, above all, considered as a sort of competitive arena in which to express antagonistic drives. (shrink)

History and memory rank as central themes in the philosophy of Friedrich Nietzsche. As one of the last philosophers of the 19th century, Nietzsche naturally belongs to the so-called ‘historical century’. The contentious exchange with the past and with antiquity – as much as the mechanisms, the dangers, and the lessons of memory and tradition – are continually examined and stand in close relationship with Nietzsche’s vision of life and his project of human development. As Jacob Burckhardt once wrote of (...) the cultural critique to his Basel colleague: "Fundamentally, you are always teaching history". Following Burckhardt’s judgment, the contributors focus on the analysis of core questions in the philosophies of history and memory, and their respective convergence in the thought of Nietzsche. The epistemological relevance of these central concepts will be thematized alongside those concerning tradition, and education. The discussion of these rich themes unifies a broad spectrum of questions, ranging from cultural memory to contemporary philosophy of mind. The contributions are revised versions of selected papers presented at the 2018 conference of the annual meeting of the Nietzsche Society in Naumburg. (shrink)